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REV-ERBα Agonist GSK4112 attenuates Fas-induced Acute Hepatic Damage in Mice

Fas-induced apoptosis is a central mechanism of hepatocyte damage during acute and chronic hepatic disorders. Increasing evidence suggests that circadian clock plays critical roles in the regulation of cell fates. In the present study, the potential significance of REV-ERBα, a core ingredient of cir...

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Detalles Bibliográficos
Autores principales: Shao, Ruyue, Yang, Yongqiang, Fan, Kerui, Wu, Xicheng, Jiang, Rong, Tang, Li, Li, Longjiang, Shen, Yi, Liu, Gang, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579287/
https://www.ncbi.nlm.nih.gov/pubmed/34790059
http://dx.doi.org/10.7150/ijms.52011