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Assessment of the Utility of Physiologically-based Pharmacokinetic Model for prediction of Pharmacokinetics in Chinese and Japanese Populations

The objective for the present analyses was to evaluate the utility of physiologically-based pharmacokinetic (PBPK) modeling for prediction of the pharmacokinetics (PK) in Chinese and Japanese populations with a panel of Pfizer internal compounds. Twelve compounds from Pfizer internal development pip...

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Detalles Bibliográficos
Autores principales: Yu, Yanke, Lin, Jian, Muto, Chieko, Li, Yinhua, Mori, Yuko, Mittapalli, Rajendar K, Tse, Susanna, Liu, Jian, Ge, Bei Kang, Liu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579302/
https://www.ncbi.nlm.nih.gov/pubmed/34790045
http://dx.doi.org/10.7150/ijms.65040