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MAD2B-mediated cell cycle reentry of podocytes is involved in the pathogenesis of FSGS

Rationale: Focal segmental glomerulosclerosis (FSGS) is characterized by the dysfunction of “post-mitotic” podocytes. The reentry of podocytes in the cell cycle will ultimately result in cell death. Mitotic arrest deficient 2-like protein 2 (MAD2B), an inhibitor of anaphase-promoting complex (APC)/c...

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Detalles Bibliográficos
Autores principales: Bao, Dian, Su, Hua, Lei, Chun-Tao, Tang, Hui, Ye, Chen, Xiong, Wei, He, Fang-Fang, Lin, Ji-Hong, Hammes, Hans-Peter, Zhang, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579434/
https://www.ncbi.nlm.nih.gov/pubmed/34803506
http://dx.doi.org/10.7150/ijbs.62238