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miRNA-223 Suppresses Mouse Gallstone Formation by Targeting Key Transporters in Hepatobiliary Cholesterol Secretion Pathway

miRNA-223 has been previously reported to play an essential role in hepatic cholesterol homeostasis. However, its role in regulation of biliary cholesterol secretion and gallstone formation remains unknown. Hence, mice with conventional knockout (KO), hepatocyte-specific knockout (ΔHepa) / knockdown...

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Detalles Bibliográficos
Autores principales: Zhao, Feng, Ma, Shiyu, Zhou, Yuling, Wei, Bailing, Hao, Zhen, Cui, Xiaolin, Xing, Lina, Liu, Gang, Jin, Lingling, Ma, Tonghui, Shi, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579439/
https://www.ncbi.nlm.nih.gov/pubmed/34803510
http://dx.doi.org/10.7150/ijbs.65485