Berberine improves insulin-induced diabetic retinopathy through exclusively suppressing Akt/mTOR-mediated HIF-1α/VEGF activation in retina endothelial cells

Background: Insulin therapy is the major treatment of glycaemic control in type I diabetes mellitus (DM) and advanced type II DM patients who fail to respond to oral hypoglycemic agents. Nonetheless, insulin therapy is deemed unsuccessful in controlling the incidence of diabetic retinopathy (DR) and...

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Detalles Bibliográficos
Autores principales: Wang, Ning, Zhang, Cheng, Xu, Yu, Tan, Hor-Yue, Chen, Haiyong, Feng, Yibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579442/
https://www.ncbi.nlm.nih.gov/pubmed/34803500
http://dx.doi.org/10.7150/ijbs.62868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579442/
https://www.ncbi.nlm.nih.gov/pubmed/34803500
http://dx.doi.org/10.7150/ijbs.62868

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