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Conformational dynamics and energetics of viral RNA recognition by lab-evolved proteins

The conserved and structured elements in viral RNA genomes interact with proteins to regulate various events in the viral life cycle and have become key targets for developing novel therapeutic approaches. We probe physical interactions between lab-evolved proteins and a viral RNA element from the H...

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Detalles Bibliográficos
Autores principales: Kumar, Amit, Vashisth, Harish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579469/
https://www.ncbi.nlm.nih.gov/pubmed/34714308
http://dx.doi.org/10.1039/d1cp03822b