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The role of pathological tau in synaptic dysfunction in Alzheimer’s diseases

Alzheimer’s disease (AD) is a neurodegenerative disease characterized by progressive cognitive decline, accompanied by amyloid-β (Aβ) overload and hyperphosphorylated tau accumulation in the brain. Synaptic dysfunction, an important pathological hallmark in AD, is recognized as the main cause of the...

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Detalles Bibliográficos
Autores principales: Wu, Moxin, Zhang, Manqing, Yin, Xiaoping, Chen, Kai, Hu, Zhijian, Zhou, Qin, Cao, Xianming, Chen, Zhiying, Liu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579533/
https://www.ncbi.nlm.nih.gov/pubmed/34753506
http://dx.doi.org/10.1186/s40035-021-00270-1