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The role of pathological tau in synaptic dysfunction in Alzheimer’s diseases
Alzheimer’s disease (AD) is a neurodegenerative disease characterized by progressive cognitive decline, accompanied by amyloid-β (Aβ) overload and hyperphosphorylated tau accumulation in the brain. Synaptic dysfunction, an important pathological hallmark in AD, is recognized as the main cause of the...
Autores principales: | Wu, Moxin, Zhang, Manqing, Yin, Xiaoping, Chen, Kai, Hu, Zhijian, Zhou, Qin, Cao, Xianming, Chen, Zhiying, Liu, Dan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579533/ https://www.ncbi.nlm.nih.gov/pubmed/34753506 http://dx.doi.org/10.1186/s40035-021-00270-1 |
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