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Assessment of genetic diversity of Plasmodium falciparum circumsporozoite protein in Sudan: the RTS,S leading malaria vaccine candidate

BACKGROUND: The currently used malaria vaccine, RTS,S, is designed based on the Plasmodium falciparum circumsporozoite protein (PfCSP). The pfcsp gene, besides having different polymorphic patterns, can vary between P. falciparum isolates due to geographical origin and host immune response. Such asp...

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Detalles Bibliográficos
Autores principales: Mohamed, Nouh Saad, AbdElbagi, Hanadi, Elsadig, Ahad R., Ahmed, Abdalla Elssir, Mohammed, Yassir Osman, Elssir, Lubna Taj, Elnour, Mohammed-Ahmed B., Ali, Yousif, Ali, Mohamed S., Altahir, Omnia, Abubakr, Mustafa, Siddig, Emmanuel Edwar, Ahmed, Ayman, Omer, Rihab Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579544/
https://www.ncbi.nlm.nih.gov/pubmed/34758827
http://dx.doi.org/10.1186/s12936-021-03971-0