MET amplification identified by next-generation sequencing and its clinical relevance for MET inhibitors

BACKGROUND: MET amplification plays an important role in the development of non-small-cell lung cancer (NSCLC) either de novo or in resistance to epidermal growth factor receptor tyrosine–kinase inhibitor (EGFR-TKI) settings. Fluorescence in situ hybridization (FISH) is the standard method for MET a...

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Detalles Bibliográficos
Autores principales: Peng, Lun-Xi, Jie, Guang-Ling, Li, An-Na, Liu, Si-Yang, Sun, Hao, Zheng, Mei-Mei, Zhou, Jia-Ying, Zhang, Jia-Tao, Zhang, Xu-Chao, Zhou, Qing, Zhong, Wen-Zhao, Yang, Jin-Ji, Tu, Hai-Yan, Su, Jian, Yan, Hong-Hong, Wu, Yi-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579577/
https://www.ncbi.nlm.nih.gov/pubmed/34758872
http://dx.doi.org/10.1186/s40164-021-00245-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579577/
https://www.ncbi.nlm.nih.gov/pubmed/34758872
http://dx.doi.org/10.1186/s40164-021-00245-y

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