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Down-regulation of EPB41L4A-AS1 mediated the brain aging and neurodegenerative diseases via damaging synthesis of NAD(+) and ATP

BACKGROUND: Aging and neurodegenerative diseases are typical metabolic-related processes. As a metabolism-related long non-coding RNA, EPB41L4A-AS has been reported to be potentially involved in the development of brain aging and neurodegenerative diseases. In this study, we sought to reveal the mec...

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Detalles Bibliográficos
Autores principales: Yang, Tingpeng, Wang, Yanzhi, Liao, Weijie, Zhang, Shikuan, Wang, Songmao, Xu, Naihan, Xie, Weidong, Luo, Cheng, Wang, Yangyang, Wang, Ziqiang, Zhang, Yaou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579638/
https://www.ncbi.nlm.nih.gov/pubmed/34758883
http://dx.doi.org/10.1186/s13578-021-00705-2