The low-complexity domains of the KMT2D protein regulate histone monomethylation transcription to facilitate pancreatic cancer progression

BACKGROUND: Liquid–liquid phase separation (LLPS) within the nucleus is directly linked to driving gene expression through transcriptional complexes. Histone lysine methyltransferase 2D (KMT2D) is widely present in many cancers. It is known to epigenetically stimulate the expression of genes associa...

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Detalles Bibliográficos
Autores principales: Li, Weihan, Wu, Lei, Jia, Hui, Lin, Zenghua, Zhong, Renhao, Li, Yukun, Jiang, Chenwei, Liu, Shifan, Zhou, Xiaorong, Zhang, Erhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579673/
https://www.ncbi.nlm.nih.gov/pubmed/34758724
http://dx.doi.org/10.1186/s11658-021-00292-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579673/
https://www.ncbi.nlm.nih.gov/pubmed/34758724
http://dx.doi.org/10.1186/s11658-021-00292-7

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