IL-7 and CCR2b Co-Expression-Mediated Enhanced CAR-T Survival and Infiltration in Solid Tumors

Chimeric antigen receptor T (CAR-T) cells are not effective in solid tumor treatment due to reduced invasion and expansion, and short survival time. This study aimed to explore whether interleukin (IL)-7 and CCR2b expression could improve GD2-CAR-T cell survival and infiltration in neuroblastoma and...

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Detalles Bibliográficos
Autores principales: Li, Guangchao, Zhang, Qing, Han, Zeping, Zhu, Yangmin, Shen, Huijuan, Liu, Zhi, Zhou, Zhao, Ding, Wen, Han, Siqi, He, Jinhua, Yin, Zhao, Zhou, Jie, Ou, Ruiming, Luo, Min, Liu, Shuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579717/
https://www.ncbi.nlm.nih.gov/pubmed/34778046
http://dx.doi.org/10.3389/fonc.2021.734593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579717/
https://www.ncbi.nlm.nih.gov/pubmed/34778046
http://dx.doi.org/10.3389/fonc.2021.734593

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