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Utilizing mouse optic nerve crush to examine CNS remyelination

In developing pro-myelination treatment, an important hurdle is the lack of reliable animal models for assessing de novo myelination in disease settings. We recently showed that regenerated axons in injured optic nerves fail to be myelinated, providing an animal model for this purpose. Here, we desc...

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Detalles Bibliográficos
Autores principales: Suter, Tracey A.C.S., Wang, Jing, Meng, Huyan, He, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579818/
https://www.ncbi.nlm.nih.gov/pubmed/34786561
http://dx.doi.org/10.1016/j.xpro.2021.100796