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Isolation and Characterization of Human Monoclonal Antibodies to Pneumococcal Capsular Polysaccharide 3

The current pneumococcal capsular polysaccharide (PPS) conjugate vaccine (PCV13) is less effective against Streptococcus pneumoniae serotype 3 (ST3), which remains a major cause of pneumococcal disease and mortality. Therefore, dissecting structure-function relationships of human ST3 pneumococcal ca...

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Detalles Bibliográficos
Autores principales: Babb, Rachelle, Doyle, Christopher R., Pirofski, Liise-anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579928/
https://www.ncbi.nlm.nih.gov/pubmed/34756090
http://dx.doi.org/10.1128/Spectrum.01446-21