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Culture-Independent Detection of Poliovirus in Stool Samples by Direct RNA Extraction

Laboratory surveillance for poliovirus (PV) relies on virus isolation by cell culture to identify PV in stool specimens from acute flaccid paralysis (AFP) cases. Although this method successfully identifies PV, it is time-consuming and necessitates the additional biorisk of growing live virus in an...

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Detalles Bibliográficos
Autores principales: Harrington, Chelsea, Sun, Hong, Jeffries-Miles, Stacey, Gerloff, Nancy, Mandelbaum, Mark, Pang, Hong, Collins, Nikail, Burns, Cara C., Vega, Everardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579935/
https://www.ncbi.nlm.nih.gov/pubmed/34756088
http://dx.doi.org/10.1128/Spectrum.00668-21