PCSK9 Activity Is Potentiated Through HDL Binding

PCSK9 (proprotein convertase subtilisin/kexin type 9) circulates in a free and lipoprotein-bound form, yet the functional consequence of the association between PCSK9 and HDL (high-density lipoprotein) remains unexplored. OBJECTIVE: This study sought to interrogate the novel relationship between PCS...

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Detalles Bibliográficos
Autores principales: Burnap, Sean A., Sattler, Katherine, Pechlaner, Raimund, Duregotti, Elisa, Lu, Ruifang, Theofilatos, Konstantinos, Takov, Kaloyan, Heusch, Gerd, Tsimikas, Sotirios, Fernández-Hernando, Carlos, Berry, Sarah E., Hall, Wendy L., Notdurfter, Marlene, Rungger, Gregorio, Paulweber, Bernhard, Willeit, Johann, Kiechl, Stefan, Levkau, Bodo, Mayr, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579991/
https://www.ncbi.nlm.nih.gov/pubmed/34601896
http://dx.doi.org/10.1161/CIRCRESAHA.121.319272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579991/
https://www.ncbi.nlm.nih.gov/pubmed/34601896
http://dx.doi.org/10.1161/CIRCRESAHA.121.319272

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