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Improvement of the antimicrobial potency, pharmacokinetic and pharmacodynamic properties of albicidin by incorporation of nitrogen atoms

The worrisome development and spread of multidrug-resistant bacteria demands new antibacterial agents with strong bioactivities particularly against Gram-negative bacteria. Albicidins were recently structurally characterized as highly active antibacterial natural products from the bacterium Xanthomo...

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Detalles Bibliográficos
Autores principales: Zborovsky, Lieby, Kleebauer, Leonardo, Seidel, Maria, Kostenko, Arseni, von Eckardstein, Leonard, Gombert, Frank Otto, Weston, John, Süssmuth, Roderich D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580050/
https://www.ncbi.nlm.nih.gov/pubmed/34881013
http://dx.doi.org/10.1039/d1sc04019g