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Improvement of the antimicrobial potency, pharmacokinetic and pharmacodynamic properties of albicidin by incorporation of nitrogen atoms
The worrisome development and spread of multidrug-resistant bacteria demands new antibacterial agents with strong bioactivities particularly against Gram-negative bacteria. Albicidins were recently structurally characterized as highly active antibacterial natural products from the bacterium Xanthomo...
Autores principales: | Zborovsky, Lieby, Kleebauer, Leonardo, Seidel, Maria, Kostenko, Arseni, von Eckardstein, Leonard, Gombert, Frank Otto, Weston, John, Süssmuth, Roderich D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580050/ https://www.ncbi.nlm.nih.gov/pubmed/34881013 http://dx.doi.org/10.1039/d1sc04019g |
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