Cargando…

Radical–anion coupling through reagent design: hydroxylation of aryl halides

The design and development of an oxime-based hydroxylation reagent, which can chemoselectively convert aryl halides (X = F, Cl, Br, I) into phenols under operationally simple, transition-metal-free conditions is described. Key to the success of this approach was the identification of a reducing oxim...

Descripción completa

Detalles Bibliográficos
Autores principales: Greener, Andrew J., Ubysz, Patrycja, Owens-Ward, Will, Smith, George, Ocaña, Ivan, Whitwood, Adrian C., Chechik, Victor, James, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580057/
https://www.ncbi.nlm.nih.gov/pubmed/34881017
http://dx.doi.org/10.1039/d1sc04748e