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Cationic helicenes as selective G4 DNA binders and optical probes for cellular imaging

The important role that G-quadruplex DNA (G4 DNA) structures play in regulating biological processes is becoming widely recognised. These structures have also been proposed to be attractive drug targets. Therefore, there has been significant interest in developing small molecules that can selectivel...

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Detalles Bibliográficos
Autores principales: Summers, Peter A., Thomas, Ajesh P., Kench, Timothy, Vannier, Jean-Baptiste, Kuimova, Marina K., Vilar, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580066/
https://www.ncbi.nlm.nih.gov/pubmed/34881015
http://dx.doi.org/10.1039/d1sc04567a