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Allelic and genotypic frequencies of NAT2, CYP2E1, and AADAC genes in a cohort of Peruvian tuberculosis patients

BACKGROUND: We determined the frequency of genetic polymorphisms in three anti‐TB drug metabolic proteins previously reported: N‐acetyltransferase 2 (NAT2), cytochrome P450 2E1 (CYP2E1), and arylacetamide deacetylase (AADAC) within a Peruvian population in a cohort of TB patients. METHODS: We genoty...

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Detalles Bibliográficos
Autores principales: Levano, Kelly S., Jaramillo‐Valverde, Luis, Tarazona, David D., Sanchez, Cesar, Capristano, Silvia, Vásquez‐Loarte, Tania, Solari, Lely, Mendoza‐Ticona, Alberto, Soto, Alonso, Rojas, Christian, Zegarra‐Chapoñan, Roberto, Guio, Heinner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580101/
https://www.ncbi.nlm.nih.gov/pubmed/34510815
http://dx.doi.org/10.1002/mgg3.1764