Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis

DNA damage reshapes the cellular transcriptome by modulating RNA transcription and processing. In cancer cells, these changes can alter the expression of genes in the immune surveillance and cell death pathways. Here, we investigate how DNA damage impacts alternative polyadenylation (APA) using the...

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Detalles Bibliográficos
Autores principales: Kunisky, Alexander K., Anyaeche, Vivian I., Herron, R. Samuel, Park, Christopher Y., Hwang, Hun-Way
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580136/
https://www.ncbi.nlm.nih.gov/pubmed/34644577
http://dx.doi.org/10.1016/j.celrep.2021.109815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580136/
https://www.ncbi.nlm.nih.gov/pubmed/34644577
http://dx.doi.org/10.1016/j.celrep.2021.109815

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