Frontotemporal Lobar Dementia Mutant Tau Impairs Axonal Transport through a Protein Phosphatase 1γ-Dependent Mechanism

Pathologic tau modifications are characteristic of Alzheimer's disease and related dementias, but mechanisms of tau toxicity continue to be debated. Inherited mutations in tau cause early onset frontotemporal lobar dementias (FTLD-tau) and are commonly used to model mechanisms of tau toxicity i...

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Detalles Bibliográficos
Autores principales: Combs, Benjamin, Christensen, Kyle R., Richards, Collin, Kneynsberg, Andrew, Mueller, Rebecca L., Morris, Sarah L., Morfini, Gerardo A., Brady, Scott T., Kanaan, Nicholas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580143/
https://www.ncbi.nlm.nih.gov/pubmed/34607969
http://dx.doi.org/10.1523/JNEUROSCI.1914-20.2021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580143/
https://www.ncbi.nlm.nih.gov/pubmed/34607969
http://dx.doi.org/10.1523/JNEUROSCI.1914-20.2021

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