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TwinCons: Conservation score for uncovering deep sequence similarity and divergence
We have developed the program TwinCons, to detect noisy signals of deep ancestry of proteins or nucleic acids. As input, the program uses a composite alignment containing pre-defined groups, and mathematically determines a ‘cost’ of transforming one group to the other at each position of the alignme...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580257/ https://www.ncbi.nlm.nih.gov/pubmed/34714829 http://dx.doi.org/10.1371/journal.pcbi.1009541 |