The use of two-sample methods for Mendelian randomization analyses on single large datasets

BACKGROUND: With genome-wide association data for many exposures and outcomes now available from large biobanks, one-sample Mendelian randomization (MR) is increasingly used to investigate causal relationships. Many robust MR methods are available to address pleiotropy, but these assume independence...

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Detalles Bibliográficos
Autores principales: Minelli, Cosetta, Del Greco M., Fabiola, van der Plaat, Diana A, Bowden, Jack, Sheehan, Nuala A, Thompson, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580269/
https://www.ncbi.nlm.nih.gov/pubmed/33899104
http://dx.doi.org/10.1093/ije/dyab084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580269/
https://www.ncbi.nlm.nih.gov/pubmed/33899104
http://dx.doi.org/10.1093/ije/dyab084

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