Evaluating the direct effects of childhood adiposity on adult systemic metabolism: a multivariable Mendelian randomization analysis

BACKGROUND: Individuals who are obese in childhood have an elevated risk of disease in adulthood. However, whether childhood adiposity directly impacts intermediate markers of this risk, independently of adult adiposity, is unclear. In this study, we have simultaneously evaluated the effects of chil...

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Detalles Bibliográficos
Autores principales: Richardson, Tom G, Mykkänen, Juha, Pahkala, Katja, Ala-Korpela, Mika, Bell, Joshua A, Taylor, Kurt, Viikari, Jorma, Lehtimäki, Terho, Raitakari, Olli, Davey Smith, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Mendelian Randomization
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580280/
https://www.ncbi.nlm.nih.gov/pubmed/33783488
http://dx.doi.org/10.1093/ije/dyab051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580280/
https://www.ncbi.nlm.nih.gov/pubmed/33783488
http://dx.doi.org/10.1093/ije/dyab051

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