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Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex

The Lon protease is the prototype of a family of proteolytic machines with adenosine triphosphatase modules built into a substrate degradation chamber. Lon is known to degrade protein substrates in a processive fashion, cutting a protein chain processively into small peptides before commencing cleav...

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Detalles Bibliográficos
Autores principales: Li, Shanshan, Hsieh, Kan-Yen, Kuo, Chiao-I, Su, Shih-Chieh, Huang, Kai-Fa, Zhang, Kaiming, Chang, Chung-I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580320/
https://www.ncbi.nlm.nih.gov/pubmed/34757797
http://dx.doi.org/10.1126/sciadv.abj9537