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Up-regulation of SIRT1 induced by 17beta-estradiol promotes autophagy and inhibits apoptosis in osteoblasts

Osteoporosis is a common systemic skeletal metabolism disorder resulting in bone fragility and increased fracture risk. Silent information regulator factor 2 homolog 1 (SIRT1) is crucial in the regulation of several biological processes, including bone metabolism, autophagy, apoptosis, and aging. Th...

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Detalles Bibliográficos
Autores principales: Wang, Yu, Mei, Runhong, Hao, Shimin, Luo, Peng, Wang, Penghao, Almatari, Yaser, Guo, Lei, Guo, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580331/
https://www.ncbi.nlm.nih.gov/pubmed/34711685
http://dx.doi.org/10.18632/aging.203639