Nmnat2 attenuates amyloidogenesis and up-regulates ADAM10 in AMPK activity-dependent manner

Amyloid-β (Aβ) accumulating is considered as a causative factor for formation of senile plaque in Alzheimer’s disease (AD), but its mechanism is still elusive. The Nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2), a key redox cofactor for energy metabolism, is reduced in AD. Accumulative e...

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Detalles Bibliográficos
Autores principales: Cheng, Xiang-Shu, Shi, Fang-Xiao, Zhao, Kun-Peng, Lin, Wang, Li, Xiao-Ying, Zhang, Jun, Bu, Yao-Yao, Zhu, Rui, Li, Xiao-Hong, Duan, Dong-Xiao, Ji, Xin-Ying, Wei, Jian-She, Wang, Jian-Zhi, Du, Jin, Zhou, Xin-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580354/
https://www.ncbi.nlm.nih.gov/pubmed/34644262
http://dx.doi.org/10.18632/aging.203634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580354/
https://www.ncbi.nlm.nih.gov/pubmed/34644262
http://dx.doi.org/10.18632/aging.203634

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