17β-Estradiol Attenuates Intracerebral Hemorrhage-Induced Blood–Brain Barrier Injury and Oxidative Stress Through SRC3-Mediated PI3K/Akt Signaling Pathway in a Mouse Model

Estrogen is neuroprotective in brain injury models, and steroid receptor cofactor 3 (SRC3) mediates estrogen signaling. We aimed to investigate whether and how SRC3 is involved in the neuroprotective effects of 17ß-estradiol (E2) in a mouse model of intracerebral hemorrhage (ICH). Ovariectomized fem...

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Detalles Bibliográficos
Autores principales: Xiao, Han, Liu, Jianyang, He, Jialin, Lan, Ziwei, Deng, Mingyang, Hu, Zhiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580490/
https://www.ncbi.nlm.nih.gov/pubmed/34491125
http://dx.doi.org/10.1177/17590914211038443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580490/
https://www.ncbi.nlm.nih.gov/pubmed/34491125
http://dx.doi.org/10.1177/17590914211038443

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