Nanoparticular CpG-adjuvanted SARS-CoV-2 S1 protein elicits broadly neutralizing and Th1-biased immunoreactivity in mice

The spike (S) protein is a leading vaccine candidate against SARS-CoV-2 infection. The S1 domain of S protein, which contains a critical receptor-binding domain (RBD) antigen, potentially induces protective immunoreactivities against SARS-CoV-2. In this study, we presented preclinical evaluations of...

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Detalles Bibliográficos
Autores principales: Lin, Hui-Tsu, Chen, Cheng-Cheung, Chiao, Der-Jiang, Chang, Tein-Yao, Chen, Xin-An, Young, Jenn-Jong, Kuo, Szu-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580573/
https://www.ncbi.nlm.nih.gov/pubmed/34774590
http://dx.doi.org/10.1016/j.ijbiomac.2021.11.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580573/
https://www.ncbi.nlm.nih.gov/pubmed/34774590
http://dx.doi.org/10.1016/j.ijbiomac.2021.11.020

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