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Integrative Genomic Analysis of Pediatric Myeloid-Related Acute Leukemias Identifies Novel Subtypes and Prognostic Indicators

Genomic characterization of pediatric patients with acute myeloid leukemia (AML) has led to the discovery of somatic mutations with prognostic implications. Although gene-expression profiling can differentiate subsets of pediatric AML, its clinical utility in risk stratification remains limited. Her...

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Detalles Bibliográficos
Autores principales: Fornerod, Maarten, Ma, Jing, Noort, Sanne, Liu, Yu, Walsh, Michael P., Shi, Lei, Nance, Stephanie, Liu, Yanling, Wang, Yuanyuan, Song, Guangchun, Lamprecht, Tamara, Easton, John, Mulder, Heather L., Yergeau, Donald, Myers, Jacquelyn, Kamens, Jennifer L., Obeng, Esther A., Pigazzi, Martina, Jarosova, Marie, Kelaidi, Charikleia, Polychronopoulou, Sophia, Lamba, Jatinder K., Baker, Sharyn D., Rubnitz, Jeffrey E., Reinhardt, Dirk, van den Heuvel-Eibrink, Marry M., Locatelli, Franco, Hasle, Henrik, Klco, Jeffery M., Downing, James R., Zhang, Jinghui, Pounds, Stanley, Zwaan, C. Michel, Gruber, Tanja A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580615/
https://www.ncbi.nlm.nih.gov/pubmed/34778799
http://dx.doi.org/10.1158/2643-3230.BCD-21-0049