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MCC950, the NLRP3 Inhibitor, Protects against Cartilage Degradation in a Mouse Model of Osteoarthritis

Osteoarthritis (OA), characterized by chronic systemic low-level inflammation and cartilage degeneration, is a type of arthritis closely associated with aging. Inflammation and aging play a pivotal role in the occurrence and progression of OA. NLRP3 inflammasome is involved in many inflammatory and...

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Detalles Bibliográficos
Autores principales: Ni, Bowei, Pei, Wenbin, Qu, Yunkun, Zhang, Rui, Chu, Xiangyu, Wang, Yingguang, Huang, Xiaojian, You, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580635/
https://www.ncbi.nlm.nih.gov/pubmed/34777685
http://dx.doi.org/10.1155/2021/4139048