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LOTUS overexpression via ex vivo gene transduction further promotes recovery of motor function following human iPSC-NS/PC transplantation for contusive spinal cord injury

Functional recovery is still limited mainly due to several mechanisms, such as the activation of Nogo receptor-1 (NgR1) signaling, when human induced pluripotent stem cell-derived neural stem/progenitor cells (hiPSC-NS/PC) are transplanted for subacute spinal cord injury (SCI). We previously reporte...

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Detalles Bibliográficos
Autores principales: Ito, Shuhei, Nagoshi, Narihito, Kamata, Yasuhiro, Kojima, Kota, Nori, Satoshi, Matsumoto, Morio, Takei, Kohtaro, Nakamura, Masaya, Okano, Hideyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580872/
https://www.ncbi.nlm.nih.gov/pubmed/34653401
http://dx.doi.org/10.1016/j.stemcr.2021.09.006