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Inactive rhomboid proteins RHBDF1 and RHBDF2 (iRhoms): a decade of research in murine models

Rhomboid proteases, first discovered in Drosophila, are intramembrane serine proteases. Members of the rhomboid protein family that are catalytically deficient are known as inactive rhomboids (iRhoms). iRhoms have been implicated in wound healing, cancer, and neurological disorders such as Alzheimer...

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Detalles Bibliográficos
Autores principales: Burzenski, Lisa M., Low, Benjamin E., Kohar, Vivek, Shultz, Leonard D., Wiles, Michael V., Hosur, Vishnu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580931/
https://www.ncbi.nlm.nih.gov/pubmed/34477920
http://dx.doi.org/10.1007/s00335-021-09910-3