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Inactive rhomboid proteins RHBDF1 and RHBDF2 (iRhoms): a decade of research in murine models
Rhomboid proteases, first discovered in Drosophila, are intramembrane serine proteases. Members of the rhomboid protein family that are catalytically deficient are known as inactive rhomboids (iRhoms). iRhoms have been implicated in wound healing, cancer, and neurological disorders such as Alzheimer...
Autores principales: | Burzenski, Lisa M., Low, Benjamin E., Kohar, Vivek, Shultz, Leonard D., Wiles, Michael V., Hosur, Vishnu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580931/ https://www.ncbi.nlm.nih.gov/pubmed/34477920 http://dx.doi.org/10.1007/s00335-021-09910-3 |
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