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De-escalation antibiotic therapy alleviates organ injury through modulation of NETs formation during sepsis

Empiric broad-spectrum antimicrobials therapy is suggested to be started immediately for sepsis patients. Empiric antimicrobial therapy should be narrowed once pathogen identification and sensitivities are established. However, the detailed mechanisms of de-escalation strategy are still unclear. Her...

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Detalles Bibliográficos
Autores principales: Duan, Zehua, Xie, Tian, Chu, Chengnan, Chen, Fang, Wang, Xinyu, Li, Jieshou, Ding, Weiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580974/
https://www.ncbi.nlm.nih.gov/pubmed/34759282
http://dx.doi.org/10.1038/s41420-021-00745-0