Circ-SIRT1 inhibits cardiac hypertrophy via activating SIRT1 to promote autophagy

Mounting studies have substantiated that abrogating autophagy contributes to cardiac hypertrophy (CH). Sirtuin 1 (SIRT1) has been reported to support autophagy and inhibit CH. However, the upstream regulation mechanism behind the regulation of SIRT1 level in CH remains unclear. Circular RNAs (circRN...

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Detalles Bibliográficos
Autores principales: Wang, Weichen, Wang, Longlong, Yang, Mengyue, Wu, Chunwei, Lan, Rui, Wang, Weiwei, Li, Yuze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580993/
https://www.ncbi.nlm.nih.gov/pubmed/34759275
http://dx.doi.org/10.1038/s41419-021-04059-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580993/
https://www.ncbi.nlm.nih.gov/pubmed/34759275
http://dx.doi.org/10.1038/s41419-021-04059-y

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