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Moderate-intensity exercise alleviates pyroptosis by promoting autophagy in osteoarthritis via the P2X7/AMPK/mTOR axis

Instability and excessive use of the knee joint can cause osteoarthritis (OA). Reasonable exercise can enhance the stability of the knee joint and prevent and relieve the occurrence and development of OA. As a key switch for inflammation, P2X purinoceptor 7 (P2X7) has attracted much attention in stu...

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Detalles Bibliográficos
Autores principales: Li, Zihao, Huang, Ziyu, Zhang, He, Lu, Jinghan, Tian, Yicheng, Piao, Shang, Lin, Zhiming, Bai, Lunhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580998/
https://www.ncbi.nlm.nih.gov/pubmed/34759265
http://dx.doi.org/10.1038/s41420-021-00746-z