Cargando…
Moderate-intensity exercise alleviates pyroptosis by promoting autophagy in osteoarthritis via the P2X7/AMPK/mTOR axis
Instability and excessive use of the knee joint can cause osteoarthritis (OA). Reasonable exercise can enhance the stability of the knee joint and prevent and relieve the occurrence and development of OA. As a key switch for inflammation, P2X purinoceptor 7 (P2X7) has attracted much attention in stu...
Autores principales: | Li, Zihao, Huang, Ziyu, Zhang, He, Lu, Jinghan, Tian, Yicheng, Piao, Shang, Lin, Zhiming, Bai, Lunhao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580998/ https://www.ncbi.nlm.nih.gov/pubmed/34759265 http://dx.doi.org/10.1038/s41420-021-00746-z |
Ejemplares similares
-
IRE1-mTOR-PERK Axis Coordinates Autophagy and ER Stress-Apoptosis Induced by P2X7-Mediated Ca(2+) Influx in Osteoarthritis
por: Li, Zihao, et al.
Publicado: (2021) -
Adrenomedullin alleviates the pyroptosis of Leydig cells by promoting autophagy via the ROS–AMPK–mTOR axis
por: Li, Ming-yong, et al.
Publicado: (2019) -
Dapagliflozin Alleviates Hepatic Steatosis by Restoring Autophagy via the AMPK-mTOR Pathway
por: Li, Liuran, et al.
Publicado: (2021) -
P2X7 Receptor Induces Pyroptotic Inflammation and Cartilage Degradation in Osteoarthritis via NF-κB/NLRP3 Crosstalk
por: Li, Zihao, et al.
Publicado: (2021) -
Betulinic acid inhibits pyroptosis in spinal cord injury by augmenting autophagy via the AMPK-mTOR-TFEB signaling pathway
por: Wu, Chenyu, et al.
Publicado: (2021)