PURPL represses autophagic cell death to promote cutaneous melanoma by modulating ULK1 phosphorylation

Uncontrolled overactivation of autophagy may lead to autophagic cell death, suppression of which is a pro-survival strategy for tumors. However, mechanisms involving key regulators in modulating autophagic cell death remain poorly defined. Here, we report a novel long noncoding RNA, p53 upregulated...

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Detalles Bibliográficos
Autores principales: Han, Shuo, Li, Xue, Wang, Ke, Zhu, Dingheng, Meng, Bingyao, Liu, Jieyu, Liang, Xiaoting, Jin, Yi, Liu, Xingyuan, Wen, Qian, Zhou, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581000/
https://www.ncbi.nlm.nih.gov/pubmed/34759263
http://dx.doi.org/10.1038/s41419-021-04362-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581000/
https://www.ncbi.nlm.nih.gov/pubmed/34759263
http://dx.doi.org/10.1038/s41419-021-04362-8

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