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PURPL represses autophagic cell death to promote cutaneous melanoma by modulating ULK1 phosphorylation

Uncontrolled overactivation of autophagy may lead to autophagic cell death, suppression of which is a pro-survival strategy for tumors. However, mechanisms involving key regulators in modulating autophagic cell death remain poorly defined. Here, we report a novel long noncoding RNA, p53 upregulated...

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Detalles Bibliográficos
Autores principales:	Han, Shuo, Li, Xue, Wang, Ke, Zhu, Dingheng, Meng, Bingyao, Liu, Jieyu, Liang, Xiaoting, Jin, Yi, Liu, Xingyuan, Wen, Qian, Zhou, Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581000/ https://www.ncbi.nlm.nih.gov/pubmed/34759263 http://dx.doi.org/10.1038/s41419-021-04362-8

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