Pluripotent stem cell derived dopaminergic subpopulations model the selective neuron degeneration in Parkinson’s disease

In Parkinson’s disease (PD), substantia nigra (SN) dopaminergic (DA) neurons degenerate, while related ventral tegmental area (VTA) DA neurons remain relatively unaffected. Here, we present a methodology that directs the differentiation of mouse and human pluripotent stem cells toward either SN- or...

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Detalles Bibliográficos
Autores principales: Oosterveen, Tony, Garção, Pedro, Moles-Garcia, Emma, Soleilhavoup, Clement, Travaglio, Marco, Sheraz, Shahida, Peltrini, Rosa, Patrick, Kieran, Labas, Valerie, Combes-Soia, Lucie, Marklund, Ulrika, Hohenstein, Peter, Panman, Lia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581055/
https://www.ncbi.nlm.nih.gov/pubmed/34678205
http://dx.doi.org/10.1016/j.stemcr.2021.09.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581055/
https://www.ncbi.nlm.nih.gov/pubmed/34678205
http://dx.doi.org/10.1016/j.stemcr.2021.09.014

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