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TDG is a pig-specific epigenetic regulator with insensitivity to H3K9 and H3K27 demethylation in nuclear transfer embryos

Pig cloning by somatic cell nuclear transfer (SCNT) frequently undergoes incomplete epigenetic remodeling during the maternal-to-zygotic transition, which leads to a significant embryonic loss before implantation. Here, we generated the first genome-wide landscapes of histone methylation in pig SCNT...

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Detalles Bibliográficos
Autores principales: Liu, Xin, Chen, Lu, Wang, Tao, Zhou, Jilong, Li, Zhekun, Bu, Guowei, Zhang, Jingjing, Yin, Shuyuan, Wu, Danya, Dou, Chengli, Xu, Tian, He, Hainan, Zhu, Wei, Yu, Longtao, Liu, Zhiting, Zhang, Xia, Chen, Zhen-Xia, Miao, Yi-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581057/
https://www.ncbi.nlm.nih.gov/pubmed/34678203
http://dx.doi.org/10.1016/j.stemcr.2021.09.012