Cargando…
TDG is a pig-specific epigenetic regulator with insensitivity to H3K9 and H3K27 demethylation in nuclear transfer embryos
Pig cloning by somatic cell nuclear transfer (SCNT) frequently undergoes incomplete epigenetic remodeling during the maternal-to-zygotic transition, which leads to a significant embryonic loss before implantation. Here, we generated the first genome-wide landscapes of histone methylation in pig SCNT...
Autores principales: | Liu, Xin, Chen, Lu, Wang, Tao, Zhou, Jilong, Li, Zhekun, Bu, Guowei, Zhang, Jingjing, Yin, Shuyuan, Wu, Danya, Dou, Chengli, Xu, Tian, He, Hainan, Zhu, Wei, Yu, Longtao, Liu, Zhiting, Zhang, Xia, Chen, Zhen-Xia, Miao, Yi-Liang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581057/ https://www.ncbi.nlm.nih.gov/pubmed/34678203 http://dx.doi.org/10.1016/j.stemcr.2021.09.012 |
Ejemplares similares
-
Coordination of zygotic genome activation entry and exit by H3K4me3 and H3K27me3 in porcine early embryos
por: Bu, Guowei, et al.
Publicado: (2022) -
Demethylation of H3K9 and H3K27 Contributes to the Tubular Renal Damage Triggered by Endoplasmic Reticulum Stress
por: Diaz-Bulnes, Paula, et al.
Publicado: (2022) -
Gadd45a promotes DNA demethylation through TDG
por: Li, Zheng, et al.
Publicado: (2015) -
Glutamate regulates gliosis of BMSCs to promote ENS regeneration through α-KG and H3K9/H3K27 demethylation
por: Fan, Mengke, et al.
Publicado: (2022) -
Hierarchical Accumulation of Histone Variant H2A.Z Regulates Transcriptional States and Histone Modifications in Early Mammalian Embryos
por: Liu, Xin, et al.
Publicado: (2022)