Plating human iPSC lines on micropatterned substrates reveals role for ITGB1 nsSNV in endoderm formation

Quantitative analysis of human induced pluripotent stem cell (iPSC) lines from healthy donors is a powerful tool for uncovering the relationship between genetic variants and cellular behavior. We previously identified rare, deleterious non-synonymous single nucleotide variants (nsSNVs) in cell adhes...

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Detalles Bibliográficos
Autores principales: Vickers, Alice, Tewary, Mukul, Laddach, Anna, Poletti, Martina, Salameti, Vasiliki, Fraternali, Franca, Danovi, Davide, Watt, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581167/
https://www.ncbi.nlm.nih.gov/pubmed/34678211
http://dx.doi.org/10.1016/j.stemcr.2021.09.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581167/
https://www.ncbi.nlm.nih.gov/pubmed/34678211
http://dx.doi.org/10.1016/j.stemcr.2021.09.017

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