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Plating human iPSC lines on micropatterned substrates reveals role for ITGB1 nsSNV in endoderm formation
Quantitative analysis of human induced pluripotent stem cell (iPSC) lines from healthy donors is a powerful tool for uncovering the relationship between genetic variants and cellular behavior. We previously identified rare, deleterious non-synonymous single nucleotide variants (nsSNVs) in cell adhes...
Autores principales: | Vickers, Alice, Tewary, Mukul, Laddach, Anna, Poletti, Martina, Salameti, Vasiliki, Fraternali, Franca, Danovi, Davide, Watt, Fiona M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581167/ https://www.ncbi.nlm.nih.gov/pubmed/34678211 http://dx.doi.org/10.1016/j.stemcr.2021.09.017 |
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