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MicroRNA‐146b‐5p promotes atrial fibrosis in atrial fibrillation by repressing TIMP4

Alteration of tissue inhibitors of matrix metalloproteinases (TIMP)/matrix metalloproteinases (MMP) associated with collagen upregulation has an important role in sustained atrial fibrillation (AF). The expression of miR‐146b‐5p, whose the targeted gene is TIMPs, is upregulated in atrial cardiomyocy...

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Detalles Bibliográficos
Autores principales: Ye, Qing, Liu, Quan, Ma, Xiaolong, Bai, Shuyun, Chen, Pengfei, Zhao, Yichen, Bai, Chen, Liu, Yang, Liu, Kemin, Xin, Meng, Zeng, Caiwu, Zhao, Cheng, Yao, Yan, Ma, Yue, Wang, Jiangang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581305/
https://www.ncbi.nlm.nih.gov/pubmed/34643044
http://dx.doi.org/10.1111/jcmm.16985