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LiCl attenuates impaired learning and memory of APP/PS1 mice, which in mechanism involves α7 nAChRs and Wnt/β‐catenin pathway

We examined the mechanism by which lithium chloride (LiCl) attenuates the impaired learning capability and memory function of dual‐transgenic APP/PS1 mice. Six‐ or 12‐month‐old APP/PS1 and wild‐type (WT) mice were randomized into four groups, namely WT, WT+Li (100 mg LiCl/kg body weight, gavage once...

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Detalles Bibliográficos
Autores principales: Xiang, Jie, Ran, Long‐Yan, Zeng, Xiao‐Xiao, He, Wen‐Wen, Xu, Yi, Cao, Kun, Dong, Yang‐Ting, Qi, Xiao‐Lan, Yu, Wen‐Feng, Xiao, Yan, Guan, Zhi‐Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8581309/
https://www.ncbi.nlm.nih.gov/pubmed/34708522
http://dx.doi.org/10.1111/jcmm.17006